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Official Full Name
Homo sapiens eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) DNA.
Background
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.
Synonyms
EEF1D; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); elongation factor 1-delta; EF 1D; FLJ20897; Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EF 1 delta; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Eukaryotic translation elongation factor 1 delta; Guanine nucleotide exchange protein; EF-1D; FP1047; EF1D, EF-1D, FP1047

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