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ecgf1

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Official Full Name
thymidine phosphorylase
Background
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]
Synonyms
TYMP; thymidine phosphorylase; TP; ECGF; ECGF1; MNGIE; MEDPS1; MTDPS1; PDECGF; hPD-ECGF; tdRPase; gliostatin; ECGF1, endothelial cell growth factor 1 (platelet derived) , MNGIE; TP, ECGF1, MNGIE, PDECGF, hPD-ECGF, TYMP