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dyx1

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Official Full Name
dyslexia susceptibility 1 candidate 1
Background
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen;receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in;neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a;susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling.;Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene;and the downstream cell cycle progression 1 (CCPG1) gene.
Synonyms
DYX1C1; dyslexia susceptibility 1 candidate 1; dyslexia susceptibility 1 candidate gene 1 protein; EKN1; FLJ37882; RD; DYX1; DYXC1; MGC70618; zgc:77853