This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen;receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in;neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a;susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling.;Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene;and the downstream cell cycle progression 1 (CCPG1) gene.