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dok5

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Official Full Name
docking protein 5
Background
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.
Synonyms
DOK5; docking protein 5; C20orf180, chromosome 20 open reading frame 180; dJ805C22.1; IRS6; IRS-6; insulin receptor substrate 6; downstream of tyrosine kinase 5; C20orf180; MGC16926

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