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Official Full Name
ADP-ribosyltransferase 4 (Dombrock blood group)
Background
This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known.
Synonyms
ART4; ADP-ribosyltransferase 4 (Dombrock blood group); ADP ribosyltransferase 4 , ADP ribosyltransferase 4 (DO blood group) , DO, Dombrock blood group; ecto-ADP-ribosyltransferase 4; CD297; DOK1; ADP ribosyltransferase 4 (DO blood group); ADP ribosyltransferase 4 (Dombrock blood group); ADP ribosyltransferase 4; ART 4; CD297 antigen; DO; Dombrock blood group carrier molecule; Ecto ADP ribosyltransferase 4; Mono ADP ribosyltransferase 4; Mono(ADP ribosyl)transferase 4; NAD(P)(+) arginine ADP ribosyltransferase 4; mono-ADP-ribosyltransferase 4; mono(ADP-ribosyl)transferase 4; ADP-ribosyltransferase 4 (DO blood group); NAD(P)(+)--arginine ADP-ribosyltransferase 4