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dmrt1

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Official Full Name
doublesex and mab-3 related transcription factor 1
Background
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like;DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining;pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific;and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene;is hemizygous.
Synonyms
DMRT1; doublesex and mab-3 related transcription factor 1; doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis 1; DMT1; DM domain expressed in testis protein 1; zgc:136676