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dkk3

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Official Full Name
dickkopf WNT signaling pathway inhibitor 3
Background
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Synonyms
DKK3; dickkopf 3 homolog (Xenopus laevis); dickkopf (Xenopus laevis) homolog 3; dickkopf-related protein 3; regulated in glioma; REIC; RIG; dkk-3; hDkk-3; dickkopf-3; RIG-like 5-6; RIG-like 7-1; dickkopf homolog 3; dickkopf homolog 3 (Xenopus laevis); lens fiber protein CLFEST4; si:dkey-80c24.6