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dhx36

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Official Full Name
DEAH (Asp-Glu-Ala-His) box polypeptide 36
Background
This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
DHX36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; DDX36, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 36; probable ATP-dependent RNA helicase DHX36; KIAA1488; MLEL1; G4 resolvase-1; MLE-like protein 1; DEAH box protein 36; DEAD/H (Asp-Glu-Ala-Asp/His) bo; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36; RNA helicase associated with AU-rich element ARE; G4R1; RHAU; DDX36

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