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dgcr8

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Official Full Name
DGCR8 microprocessor complex subunit
Background
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Synonyms
DGCR8; DGCR8 microprocessor complex subunit; Gy1; pasha; DGCRK6; C22orf12; microprocessor complex subunit DGCR8; DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8; C22orf12, chromosome 22 open reading frame 12; wu:fc23f08; wu:fc38f06; si:ch211-106a19.4