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ddx54

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Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Background
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif;Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving;alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome;and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be;involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this;gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity.;Alternative splice variants that encode different isoforms have been found for this gene.
Synonyms
DDX54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; ATP-dependent RNA helicase DDX54; APR 5; DP97; MGC2835; DEAD box protein 54; DEAD box helicase 97 KDa; DEAD box RNA helicase 97 kDa; ATP-dependent RNA helicase DP97; chunp6913; zgc:111908; ATP-dependent RNA helicase

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