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Official Full Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
Background
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Synonyms
DDOST; dolichyl-diphosphooligosaccharide--protein glycosyltransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; KIAA0115; MGC2191; OK/SW-cl.45; OST; OST48; WBP1; AGE R1; DDOST 48 kDa subunit; Dolichyl-diphosphooligosaccharide-protein glycosyltransferase; EC 2.4.1.119; Oligosaccharyl transferase 48 kDa subunit; RP23-25C1.4; wu:fa11d01; zgc:66068; zgc:77478; advanced glycation endproduct receptor 1; oligosaccharyltransferase 48 kDa subunit; dolichyl-diphosphooligosaccharide-protein glycotransferase; AGER1; OKSWcl45; dolichyl diphosphooligosaccharide protein glycosyltransferase; CDG1R; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); OST 50 kDa subunit; oligosaccharyl transferase 48 kD; oligosaccharyl transferas

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