The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
DCXR; dicarbonyl/L-xylulose reductase; L-xylulose reductase; DCR; KIDCR; SDR20C1; short chain dehydrogenase/reductase family 20C; member 1; carbonyl reductase 2; carbonyl reductase II; sperm surface protein P34H; kidney dicarbonyl reductase; short chain d; short chain dehydrogenase/reductase family 20C, member 1; XR; HCR2; P34H; HCRII; XR, DCR, HCR2, P34H, HCRII, KIDCR, SDR20C1; DER; D-erythrulose reductase; probable L-xylulose reductase; wu:fa12f09; zgc:111977