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dars2

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Official Full Name
aspartyl-tRNA synthetase 2, mitochondrial
Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
Synonyms
DARS2; aspartyl-tRNA synthetase 2, mitochondrial; aspartyl-tRNA synthetase, mitochondrial; aspartate tRNA ligase 2; mitochondrial; FLJ10514; Aspartate tRNA ligase; Aspartyl tRNA synthetase 2 (mitochondrial); AspRS; LBSL; MT ASPRS; RP3 383J4.2; aspartate tRNA ligase 2, mitochondrial; MT-ASPRS; RP3-383J4.2; aspartate--tRNA ligase, mitochondrial; LBSL, ASPRS, MT-ASPRS, RP3-383J4.2

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