Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)


Official Full Name
dystroglycan 1 (dystrophin-associated glycoprotein 1)
Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010]
DAG1; dystroglycan 1 (dystrophin-associated glycoprotein 1); A3a; DAG; AGRNR; 156DAG; MDDGC7; MDDGC9; dystroglycan; alpha dystroglycan; beta dystroglycan; dystrophin associated glycoprotein 1; FLJ51254; A3a, DAG, AGRNR, 156DAG, MDDGC7; dystroglycan 1; wu:fb83d06; wu:fi25f06; wu:fi37b08; zgc:109786; dystrophin-associated glycoprote; dystrophin-associated glycoprotein 1

Cat.No. Product Name Price
CLKO-0994DAG1 KO Cell Lysate-HEK293TInquriy
CLOE-0262Human DAG1 HEK293 Cell LysateInquriy

Related Links

Receive a quote or more information about next generation yeast two-hybrid screening services.

Skeptical of NGS-yeast two-hybrid screening? Interested, but need more information? Ready to buy, but need a quote? Contact us for more information or to request a quote.

Request a quote today!