C-X-C motif chemokine 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) and B cell-attracting chemokine 1 (BCA-1), is a 109 amino acid secreted protein that belongs to the intercrine alpha (chemokine CxC) family. It functions as a chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. CXCL13 does not induce calcium release in B-lymphocytes. It binds to BLR1/CXCR5. The highest level of CXCL13 is found in the liver, followed by spleen, lymph node, appendix and stomach. Low level of CXC13 is found in salivary gland, mammary gland, and fetal spleen.
ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13; B-cell chemoattractant; B-cell-attracting chemokine 1; B-cell-homing chemokine (ligand for Burkitts lymphoma receptor-1); B-lymphocyte chemoattractant; C-X-C motif chemokine 13; CXC chemokine BLC; b cell-attracting chemokine 1; b lymphocyte chemoattractant; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); small-inducible cytokine B13; CXCL13; chemokine (C-X-C motif) ligand 13; SCYB13, small inducible cytokine B subfamily (Cys X Cys motif), member 13 (B cell chemoattractant); B cell chemoattractant; BCA 1