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cul7

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Official Full Name
cullin 7
Background
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
CUL7; Cullin-7; dJ20C7.5; KIAA0076; cullin 7; CUL-7