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crtac1

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Official Full Name
cartilage acidic protein 1
Background
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.
Synonyms
CRTAC1; cartilage acidic protein 1; ASPIC1; CEP 68; FLJ10320; 68 kDa chondrocyte expressed protein; 68 kDa chondrocyte-expressed protein; Acidic secreted protein in cartilage; ASPIC; Cartilage acidic protein 1 precursor; CEP-68; CEP68; CRAC1_HUMAN; Protein CRTAC1-B; W307; chondrocyte expressed protein 68 kDa CEP-68

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