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crot

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Official Full Name
carnitine O-octanoyltransferase
Background
This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
Synonyms
CROT; carnitine O-octanoyltransferase; peroxisomal carnitine O-octanoyltransferase; COT; Carnitine O octanoyltransferase; OCTC_HUMAN; Peroxisomal carnitine acyltransferase; Peroxisomal carnitine O octanoyltransferase; OTTHUMP00000161500; OTTHUMP00000205461; OTTHUMP00000205463; zgc:110643