Official Full Name
This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
CROT; carnitine O-octanoyltransferase; peroxisomal carnitine O-octanoyltransferase; COT; Carnitine O octanoyltransferase; OCTC_HUMAN; Peroxisomal carnitine acyltransferase; Peroxisomal carnitine O octanoyltransferase; OTTHUMP00000161500; OTTHUMP00000205461; OTTHUMP00000205463; zgc:110643