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crkl

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Official Full Name
v-crk avian sarcoma virus CT10 oncogene homolog-like
Background
CrkL, a 39 kDa adaptor protein, has a key regulatory role in hematopoietic cells. CrkL has one SH2 and two SH3 domains, with 60% homology to CrkII (1). The amino-terminal SH3 domain of CrkL binds proteins such as C3G, SOS, PI3K, c-Abl and BCR/Abl. The SH2
Synonyms
CRKL; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v crk avian sarcoma virus CT10 oncogene homolog like; crk-like protein; Crkol; AA589403; AI325100; 1110025F07Rik; v-crk avian sarcoma virus CT10 oncogene homolog-like; zgc:63469; wu:fa55g05; wu:fj60e01; v-crk sarcoma virus CT10 oncogene homolog-like