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crbn

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Official Full Name
cereblon
Background
This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
CRBN; cereblon; mental retardation, non syndromic, autosomal recessive, 2A , MRT2A; protein cereblon; 2900045O07Rik; AF229032; AW108261; piL; 2610203G15Rik; DKFZp781K0715; MGC27358; MRT2A; OTTHUMP00000209555; Protein x 0001; MRT2; zgc:92404; zcrbn