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cradd

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Official Full Name
CASP2 and RIPK1 domain containing adaptor with death domain
Background
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008]
Synonyms
CRADD; CASP2 and RIPK1 domain containing adaptor with death domain; MRT34; RAIDD; death domain-containing protein CRADD; death adaptor molecule RAIDD; caspase and RIP adaptor with death domain; RIP-associated protein with a death domain; RIP-associated ICH1/CED3-homologous protein with death domain; RIP associated ICH1/CED3 homologous protein with death domain; MGC9163; zgc:101717