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col8a2

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Official Full Name
collagen, type VIII, alpha 2
Background
This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.
Synonyms
COL8A2; collagen, type VIII, alpha 2; FECD; collagen alpha-2(VIII) chain; PPCD; PPCD2; FLJ00201; MGC116970; MGC116972; AI429819; FECD1; MGC90765; RP23-113P22.2; RP4-665N4.3; endothelial collagen; collagen VIII, alpha-2 polypeptide; dJ665N4.1 (collagen type VIII alpha 2); si:ch211-197n10.4

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