Official Full Name
connector enhancer of kinase suppressor of Ras 2
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
CNKSR2; connector enhancer of kinase suppressor of Ras 2; CNK2; KIAA0902; KSR2; CNK homolog protein 2; connector enhancer of KSR2; connector enhancer of KSR 2; membrane-associated guanylate kinase-interact; membrane-associated guanylate kinase-interacting protein; MAGUIN