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cmbl

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Official Full Name
carboxymethylenebutenolidase homolog (Pseudomonas)
Background
CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010
Synonyms
CMBL; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase like (Pseudomonas); carboxymethylenebutenolidase homolog; FLJ23617; CMBL_HUMAN; carboxymethylenebutenolidase-like (Pseudomonas); JS-1; im:7158043; zgc:171683