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clnk

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Official Full Name
cytokine-dependent hematopoietic cell linker
Background
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the;regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR);signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 (PubMed;10562326); Goitsuka et al., 2000, 2001 (PubMed 10744659) (PubMed 11463797)).
Synonyms
CLNK; cytokine-dependent hematopoietic cell linker; mast cell immunoreceptor signal transducer; MIST; MGC35197