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clint1

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Official Full Name
clathrin interactor 1
Background
This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants.
Synonyms
CLINT1; clathrin interactor 1; CLINT; ENTH; EPNR; KIAA0171; epsinR; epsin 4; enthoprotin; epsin-related protein; clathrin interacting protein localized in the trans-Golgi region; EPN4; FLJ46753