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clec14a

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Official Full Name
C-type lectin domain family 14, member A
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this;family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling,;glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell;adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence;at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor;vascular targeting.
Synonyms
CLEC14A; C-type lectin domain family 14, member A; C14orf27, chromosome 14 open reading frame 27; C-type lectin domain family 14 member A; C type lectin domain family 14, member A; C14orf27; CEG1; ClECT and EGF like domain containing protein; EGFR5; Epidermal growth factor receptor 5; EGFR-5; ClECT and EGF-like domain containing protein; zgc:66439; wu:fi03a12; crl

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