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clcnkb

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Official Full Name
chloride channel, voltage-sensitive Ka
Background
This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
CLCNKA; chloride channel Ka; chloride channel protein ClC-Ka; hClC Ka; MGC61490; C75963; Chloride channel kidney A; Chloride channel protein ClC Ka; ClC K1; CLCK1; MGC93313; RP23-308N2.5; chloride channel, kidney, A; ClC-K1; hClC-Ka; CLCNKB