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chmp4a

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Official Full Name
charged multivesicular body protein 4A
Background
CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are;components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of;surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and;cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and;regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).
Synonyms
CHMP4A; charged multivesicular body protein 4A; C14orf123, chromatin modifying protein 4A , chromosome 14 open reading frame 123; HSPC134; VPS32A; C14orf123; Chromatin modifying protein 4a; SHAX2; SNF7 homolog associated with Alix-2; Snf7 homologue associated with Alix 2; vacuolar protein sorting-associated protein 32-1; SNF7; CHMP4; CHMP4B; SNF7-1; VPS32-1; FLJ61658; MGC142093; MGC142095

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