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chmp2a

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Official Full Name
charged multivesicular body protein 2A
Background
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are;components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of;surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and;cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and;regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).
Synonyms
CHMP2A; charged multivesicular body protein 2A; chromatin modifying protein 2A; BC 2; CHMP2; putative breast adenocarcinoma marker (32kD); VPS2; VPS2 homolog A (S. cerevisiae); VPS2A; BC2; hVps2 1; putative breast adenocarcinoma marker; Putative breast adenocarcinoma marker BC2; Vacuolar protein sorting associated protein 2 1; Vps2 1; vps2-1; hVps2-1; VPS2 homolog A; chromatin-modifying protein 2a; putative breast adenocarcinoma marker BC-2; vacuolar protein sorting-associated protein 2-1; BC-2; BC-2, BC2, CHMP2, VPS2, VPS2A, CHMP2A