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chmp1b

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Official Full Name
charged multivesicular body protein 1B
Background
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are;components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of;surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and;cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and;regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).
Synonyms
CHMP1B; charged multivesicular body protein 1B; chromatin modifying protein 1B; C18orf2; CHMP1.5; Vps46B; 2810405I11Rik; CHM1B_HUMAN; Chromatin-modifying protein 1b; hVps46-2; Vacuolar protein sorting-associated protein 46-2; Vps46-2; vacuolar protein sorting 46-2; C10orf2; C18-ORF2; fb10c03; zgc:56134; wu:fb10c03