This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.
FOXN3; forkhead box N3; C14orf116, checkpoint suppressor 1 , CHES1, chromosome 14 open reading frame 116; forkhead box protein N3; C14orf116; Checkpoint suppressor 1; CHES1; FXN3; PRO1635; OTTHUMP00000244668; OTTHUMP00000244669; OTTHUMP00000244670; OTTHUMP00000244769; zgc:136571