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cep250

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Official Full Name
centrosomal protein 250kDa
Background
This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome.
Synonyms
CEP250; centrosomal protein 250kDa; centrosomal protein 2 , CEP2; centrosome-associated protein CEP250; C NAP1; 250 kDa centrosomal protein; centrosomal protein, 250-KD; centrosome associated protein; centrosomal Nek2-associated protein 1; CEP2; CNAP1; C-