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centd3

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Official Full Name
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Background
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined.
Synonyms
ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3; centaurin, delta 3 , CENTD3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; DRAG1; FLJ21065; Ankyrin repeat and plekstrin homology domains containing protein 3; ARAP 3; ARF GAP; ARF-GAP RHO-GAP ankyrin repeat and plekstrin homology domains containing protein 3; Phosphoinositide binding protein; PtdIns 3 4 5 P3 binding protein; RHO GAP; cnt-d3; centaurin-delta-3; centaurin, delta 3; PtdIns(3,4,5)P3-binding protein; Arf and Rho GAP adapter protein 3; ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3; CENTD3