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cenpa

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Official Full Name
centromere protein A
Background
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.
Synonyms
CENPA; centromere protein A; Cenp-A; histone H3-like centromeric protein A; centrosomin A; centromere autoantigen A; centromere protein A (17kD) , centromere protein A, 17kDa; CenH3; CENP A; centromere specific histone; histone H3 like centromeric protein A; centromere protein A, 17kDa; centromere-specific histone; CenH3, CENP-A; ggCENP-A