This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins.;The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a;transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal;tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral;absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological;organization of liver and intestine. Alternative splicing results in multiple transcript variants.
CDH17; cadherin 17, LI cadherin (liver-intestine); cadherin-17; cadherin; HPT 1; LI cadherin; LI-cadherin; cadherin-16; HPT-1 cadherin; liver-intestine cadherin; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; human intestina; human intestinal peptide-associated transporter HPT-1; HPT1; CDH16; HPT-1; FLJ26931; MGC138218; MGC142024; cb903; fb65d02; wu:fb65d02