The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the;initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It;localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The;subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks.;Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional;control mechanism involving E2F proteins.
CDC6; cell division cycle 6 homolog (S. cerevisiae); CDC6 (cell division cycle 6, S. cerevisiae) homolog , CDC6 cell division cycle 6 homolog (S. cerevisiae) , CDC18L; cell division control protein 6 homolog; p62(cdc6); CDC6-related protein; cdc18-relate; im:7145727; zgc:174506