Official Full Name
CDC42 effector protein (Rho GTPase binding) 4
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
CDC42EP4; CDC42 effector protein (Rho GTPase binding) 4; cdc42 effector protein 4; binder of Rho GTPases 4; BORG4; CEP4; KAIA1777; MGC3740; MGC17125; BORG4_HUMAN; BORG4, CEP4, KAIA1777, MGC17125, MGC3740, CDC42EP4