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cd40lg

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Official Full Name
CD40 ligand
Background
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Synonyms
CD40LG; CD40 ligand; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40-L; CD40 antigen ligand; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5; tu; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; putative CD154 (CD40 ligand); tumor necrosis factor ligand superfamily member 5; CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)

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