Official Full Name
chemokine (C-C motif) receptor 4
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
CCR4; chemokine (C-C motif) receptor 4; LESTR; Sdf1r; CHEMR1; Cmkbr4; C-C CKR-4; C-C chemokine receptor type 4; fusin; chemokine (C-C) receptor 4; leukocyte-expressed seven-transmembrane-domain receptor; CC CKR 4; CD194; ChemR13; CKR4; k5 5; CCR-4; K5-5; CC-CKR-4; HGCN:14099; MGC88293