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ccl4l2

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Official Full Name
Homo sapiens chemokine (C-C motif) ligand 4-like 2 DNA.
Background
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Synonyms
CCL4L2; chemokine (C-C motif) ligand 4-like 2; CC chemokine ligand 4L2; CC chemokine ligand 4L1d2; lymphocyte activation gene 1; macrophage inflammatory protein-1b2; chemokine (C-C motif) ligand 4-like 1, telomeric; CCL4L; SCYA4L; AT744.2; CCL4L, SCYA4L, AT744.2

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