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ccbe1

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Official Full Name
collagen and calcium binding EGF domains 1
Background
This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans.
Synonyms
CCBE1; collagen and calcium binding EGF domains 1; collagen and calcium-binding EGF domain-containing protein 1; FLJ30681; KIAA1983; CCBE 1; CCBE1_HUMAN; Collagen and calcium binding EGF domain containing protein 1; Full of fluid protein homolog; MGC50861; UNQ1921/PRO4395; fof; full of fluid protein

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