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cby1

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Official Full Name
chibby homolog 1 (Drosophila)
Background
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A; CBY, arb1, PGEA1, C22orf2, PIGEA14, PIGEA-14, HS508I15A; CBY1; chibby homolog 1 (Drosophila); protein chibby homolog 1; LRP; fe37g01; wu:fe37g01; leucine-rich protein

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