The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
CBR4; carbonyl reductase 4; carbonyl reductase family member 4; FLJ14431; SDR45C1; short chain dehydrogenase/reductase family 45C; member 1; 3 oxoacyl [acyl carrier protein] reductase; 3-oxoacyl-[acyl-carrier-protein] reductase; Carbonic reductase 4; CBR 4; CBR4_HUMAN; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; short chain dehydrogenase/reductase family 45C, member 1; zgc:77144; im:6908596