Official Full Name
calsequestrin 2 (cardiac muscle)
The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin;is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding;protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular;tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease;characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
CASQ2; calsequestrin 2 (cardiac muscle); calsequestrin-2; PDIB2; calsequestrin, cardiac muscle isoform; calsequestrin 2, fast-twitch, cardiac muscle; FLJ26321; FLJ93514; CASQ1; aspartactin; calsequestrin-1; calsequestrin homologue; laminin-binding protein; calsequestrin, skeletal muscle isoform; calsequestrin 2; zgc:86817; wu:fa02h03