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casp8ap2

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Official Full Name
caspase 8 associated protein 2
Background
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
Synonyms
CASP8AP2; caspase 8 associated protein 2; CED-4; FLASH; RIP25; CASP8-associated protein 2; human FLASH; FLASH homolog RIP25; FLICE associated huge; CASP8 associated protein 2; FLICE-associated huge protein; fc74h10; wu:fc74h10; zgc:113449