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casc4

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Official Full Name
cancer susceptibility candidate 4
Background
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene.
Synonyms
CASC4; cancer susceptibility candidate 4; protein CASC4; DKFZp459F1927; H63; Cancer susceptibility candidate gene 4 protein; CASC4_HUMAN; Gene associated with HER-2/neu overexpression; MGC74708; cancer susceptibility candidate gene 4 protein homolog