Official Full Name
cancer susceptibility candidate 3
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.
CASC3; cancer susceptibility candidate 3; protein CASC3; BTZ; MLN51; Barentsz; Barentsz protein; Cancer susceptibility candidate gene 3 protein; CASC3_HUMAN; Metastatic lymph node 51; Metastatic lymph node gene 51 protein; Metastatic lymph node protein 51; MLN 51; MLN 51 protein; Protein barentsz; Protein MLN 51; drMLN51; protein MLN 51 homolog; metastatic lymph node protein 51 homolog; cancer susceptibility candidate gene 3 protein homolog