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capg

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Official Full Name
capping protein (actin filament), gelsolin-like
Background
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described.
Synonyms
CAPG; capping protein (actin filament), gelsolin-like; AFCP; macrophage-capping protein; macrophage capping protein; MCP; Actin capping protein GCAP39; Actin regulatory protein CAP G; Capping protein (actin filament) gelsolin like; Capping protein gelsolin like; gCap39; Gelsolin like capping protein; mbh1; Myc basic motif homolog 1; OTTHUMP00000203056; OTTHUMP00000203057; OTTHUMP00000203058; OTTHUMP00000203059; OTTHUMP00000203060; OTTHUMP00000203063; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein C; actin-regulatory protein CAP-G; AFCP, MCP, CAPG