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calr3

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Official Full Name
calreticulin 3
Background
The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones;localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen,;however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is;specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been;associated with familial hypertrophic cardiomyopathy.
Synonyms
CALR3; calreticulin 3; calreticulin-3; calsperin; cancer/testis antigen 93; CRT2; CT93; FLJ25355; MGC26577; CALR 3; Calreticulin 2; Calreticulin2; Calreticulin3; calreticulin-2; CMH19

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